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Quantitative analysis will be performed in R (the R Project, V.4.2.2.) and Stata V.16.1 (StataCorp, The College Station, TX, USA). We will summarise the characteristics of the study, the number of patients and the information concerning the treatment option descriptively. When quantitative analysis is not possible, we will describe the results narratively. All outcome measures of interest will be scaled for the data synthesis to achieve a uniform scale.
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