Abbreviations: CPAP — continuous positive airway pressurenHF — nasal high-flow therapyRCT — randomized controlled trial In this issue of Pediatrics, Huang et al1 conduct an economic evaluation analyzing data from the High-Flow Use in Non-Tertiary Centers for Early Respiratory Distress (HUNTER) trial2 comparing the cost-effectiveness of “bubble” continuous positive airway pressure (CPAP) with nasal high-flow therapy (nHF) in infants ≥31 weeks’ gestation and ≥1200 g receiving care in Australian...