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Lede Lin

As seen in: Nature, Wiley Online Library, MDPI
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Articles by Lede Lin

Biomechanical regulation of bladder injury and repair

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By Jiawei Chen, Yuanzhuo Chen, Xingpeng Di, Xiao Cheng Zeng, Lede Lin, Banghua Liao, Hong Shen, Liao Peng, tao jin, Deyi Luo, Sihong Shen
| Nature Verified
Abstract The urinary bladder is a hollow, muscular organ that functions to store and void urine cyclically. The bladder has a dynamic mechanical environment owing to its cyclical expansion and contraction, along with the accumulation and outflow of urine.
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A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

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By Wei Wang, Ran Yan, Lede Lin, Lei Xiang
| Wiley Online Library Verified
1 Introduction Fibrosis represents a pathological process characterized by tissue repair and scarring, strongly associated with chronic inflammatory responses and other underlying mechanisms.[1] Within the field of urology, bladder dysfunction is frequently linked to fibrotic remodeling.[2] The development of fibrosis in the bladder leads to impaired contractility of the detrusor muscle, resulting in the inability to voluntarily void among affected patients.
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Adrenocorticotropic hormone application lowered aldosterone/cortisol value on dominant side without superior surgical outcomes during adrenal venous sampling

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By Lede Lin, Huiling Chen Verified, Yu Chi Liu, Zhihong Liu
| Wiley Online Library Verified
Abstract Adrenal venous sampling (AVS) is thought to be the gold standard for primary aldosteronism (PA) subtype discrimination, during which the application of adrenocorticotropic hormone (ACTH) arouses heated debate. We aimed to identify the effect of ACTH on AVS and surgical outcomes. After propensity score matching (PSM), a total of 220 patients diagnosed with PA and completed AVS were included (110 without ACTH stimulation and 110 with ACTH stimulation).
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Immunotherapy vs. Chemotherapy in Subsequent Treatment of Malignant Pleural Mesothelioma: Which Is Better?

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By Xiaotong Guo, Lede Lin, Jiang Zhu
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Xiaotong Guo 1,†, Lede Lin 2,† and Jiang Zhu 1,* 1 Department of Thoracic Oncology, West China Hospital, Sichuan University, Chengdu 610041, China 2 Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu 610041, China * Author to whom correspondence should be addressed.
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