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Leopold D Tientcheu on Muck Rack

Leopold D Tientcheu

As seen in: Color Research & Application, Nature
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Articles by Leopold D Tientcheu

Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis

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By Nicholas J Andreas, Leopold D Tientcheu, Beate Kampmann, Abdou Sillah
| Nature Verified
Abstract We applied a metabonomic strategy to identify host biomarkers in serum to diagnose paediatric tuberculosis (TB) disease. 112 symptomatic children with presumptive TB were recruited in The Gambia and classified as bacteriologically-confirmed TB, clinically diagnosed TB, or other diseases. Sera were analysed using 1H nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). Multivariate data analysis was used to distinguish patients with TB from other diseases.
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Immunological consequences of strain variation within the Mycobacterium Tuberculosis complex

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By Beate Kampmann, Robert Wilkinson, Leopold D Tientcheu, Anastasia Koch, Mthawelenga Ndengane, Genevieve Andoseh
| Color Research & Application Verified
In 2015 there were an estimated 10.4 million new cases of Tuberculosis (TB) globally, making it one of the leading causes of death due to an infectious disease. TB is caused by members of the Mycobacterium tuberculosis complex (MTBC), with human disease resulting from infection by M. tuberculosis sensu strico and M. africanum.
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