Abstract We report a case of a 65-year-old Chinese man with chronic systemic inflammation, who presented with nephrotic syndrome and renal insufficiency, along with elevated serum anti-glomerular basement membrane (GBM) antibody titers, yet lacked the typical clinical features of rapidly progressive glomerulonephritis (GN). Renal biopsy demonstrated AA amyloid deposition in the glomerular mesangium, crescent formation in 33% of glomeruli, and patchy immunoglobulin G (IgG) staining.
