1 INTRODUCTION The landmark PROMIS study established magnetic resonance imaging of the prostate (MRI-P) followed by prostate biopsy as the gold standard diagnostic pathway for men with suspected prostate cancer (PCa).1 Prospective studies have since demonstrated that MRI-P followed by targeted prostate biopsy, is non-inferior to systematic biopsies.2, 3 Despite this evidence, performing targeted biopsies alone after MRI-P continues to be considered controversial.4, 5 Concerns about MRI-P...