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Abstract Colorectal cancer (CRC) is frequently accompanied by dysregulation of lipid metabolism. However, how sphingolipid metabolism–associated regulators influence key cellular processes in CRC remains unclear. By integrating TCGA and GEO datasets with differential expression analysis and machine learning, we identified SMPD3 as a candidate regulator of CRC progression and antitumor immunity.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
