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Abstract Left atrial (LA) and ventricular (LV) functional impairment often co-exist in patients with heart failure (HF). However, some patients with HF have a disproportionate LA or LV dysfunction. We aimed to characterize patients with predominant LA and LV myopathy in a cohort of patients with chronic HF across the spectrum of LV ejection fraction (LVEF).
Previously, details of the study design, criteria for the enrollment and selection of patients have been published [8, 9]. Briefly, the current study included a total of 469 patients with chronic HF from a nationwide, prospective, multi-center, observational HF study. Of these 469 patients, 95 patients were excluded due to ineligible DICOM format echocardiographic files for post-offline analysis or because LA reservoir or LVGLS to define the LA/LV myopathy phenotypes could not be obtained.
Hiromi W. Koh1, 2, Anna Pilbrow3, Sock Hwee Tan2, 4, Qing Zhao2, Peter I. Benke5, Bo Burla5, Federico Torta5, John W. Pickering3, Richard Troughton3, Christopher Pemberton3, Wern-Miin Soo4, 6, Lieng Hsi Ling4, 6, Robert N. Doughty7, Hyungwon Choi2, Markus R. Wenk5, 8, A. M. Richards2* and Mark Y.
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