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Articles by Linbin Wang
Bed nucleus of the stria terminalis-nucleus accumbens stimulation for depression: A randomized, double-blind, crossover trial
Keywords depression deep brain stimulation clinical trial magnetic resonance imaging functional connectivity Introduction Depression is a leading cause of avoidable suffering in the world.1,2 Approximately one-third of patients meet the criteria for treatment-resistant depression (TRD), for whom medication, cognitive behavioral therapy, and electroconvulsive therapy showed minimal effects.3 By directly modulating deep brain structures and neural circuits, deep brain stimulation (DBS) presents...
Prefrontal–bed nucleus of the stria terminalis physiological and neuropsychological biomarkers predict therapeutic outcomes in depression - Nature Communications
Abstract Therapeutic options for refractory depression are urgently needed. We conducted a deep brain stimulation (DBS) randomized controlled trial of the bed nucleus of the stria terminalis (BNST), an extended amygdala structure, and nucleus accumbens (NAc) in 26 refractory depression patients to assess treatment efficacy and predictors of response. BNST-NAc DBS had a 50% depression response rate and 35% remission rate in the open-label phase.
An efficient cooling solution with 3D interconnected graphene architectures for passive heat dissipation
An efficient cooling solution with 3D interconnected graphene architectures for passive heat dissipation Yangziwan Weng, Sicheng Wu, Linbin Wang, Weiyun Zhao, Yi Jiang and Yuan Deng Abstract Efficient passive cooling for miniaturized and integrated electronic devices could enhance device reliability with reduced energy consumption. The realization of such technology calls for highly efficient passive heat dissipation materials.
Frontiers | Case report: Combined therapy of bilateral subthalamic nucleus deep brain stimulation and spinal cord stimulation significantly improves motor function in a patient with multiple system atrophy with predominant parkinsonism
Introduction Multiple system atrophy with predominant parkinsonism (MSA-P) presents with parkinsonian symptoms as its prominent manifestation and may have limited response to levodopa. It is a highly incapacitating disease with a mean survival of 6–10 years (O’Sullivan et al., 2008; Wenning et al., 2013), and symptomatic therapy is still limited (Meissner et al., 2019).
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