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Articles by Lingdan Chen
Severe Immune-Related Adverse Events Associated with Durable Antitumor Responses Following Immune Checkpoint Inhibitor Therapy: Two Case Reports
Introduction Immune checkpoint inhibitors (ICIs), by blocking negative regulatory signals on T cells, have revolutionized the treatment paradigm for advanced cancers by reinvigorating antitumor immunity.1,2 However, the overactivation of the immune system acts as a “double-edged sword”, potentially harming the host while attacking the tumor, leading to immune-related adverse events (irAEs).3 In the clinical practice of managing these toxicities, an intriguing observation has emerged: patient...
Stroke in pulmonary hypertension: Is it predictable or preventable?
Lingdan Chen Lingdan Chen Affiliations State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangdong Key Laboratory of Vascular Medicine, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510120, China Search for articles by this author Wenjun He Wenjun He Affiliations State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Health, Guangdong Key Laboratory of Vascular Medicine, The First Affiliated...
Macrophage migration inhibitory factor (MIF) elevation in acute myocardial infarction is arteriogenic
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. We have read with great interest of the recently published article entitled “Macrophage migration inhibitory factor (MIF) is associated with degree of collateralization in patients with totally occluded coronary arteries” by Di Serafino et al. [1].
Modulation of EPC: A new hope for pulmonary artery hypertension treatment
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. We have read with great interest of the recently published article entitled “Effect of targeted therapy on circulating progenitor cells in precapillary pulmonary hypertension” by García-Lucio J et al. [1].
Can treprostinil-induced early gastrointestinal side effects serve as predictors of pulmonary arterial hypertension prognosis?
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Treprostinil is a synthetic analog of prostacyclin (PGI2), which has been used for severe pulmonary arterial hypertension (PAH). In a recent issue of International Journal of Cardiology, Leary et al.
VEGF165b elevation in pulmonary arterial hypertension patients, causative or adaptive?
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. We have read with great interest of the recently published article entitled “Association between levels of anti-angiogenic isoform of vascular endothelial growth factor (VEGF) A and pulmonary hypertension” by Suzuki S et al. [1].
MicroRNA-93 upregulation in coronary artery disease is potentially adaptive
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. We have read with great interest the recently published article entitled “miRNA-93-5p and other miRNAs as predictors of coronary artery disease and STEMI” by O?Sullivan JF et al [1].
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