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Articles by Lingyi Lu
Association between smoking and the clinical status of adult patients with moderate-severe atopic dermatitis in the China Atopic Dermatitis Registry (ChinaSTAD): a cross-sectional study
Abstract Background: Atopic dermatitis (AD) is a common inflammatory skin disease influenced by multiple factors such as genetic, environmental and lifestyle factors. This study explored the association between smoking and AD. Methods: The China Atopic Dermatitis Registry (ChinaSTAD) is a nationwide observational registry of patients with moderate to severe AD in China. We conducted a cross-sectional analysis of adult patients enrolled from July 2021 to April 2023 across 26 provinces.
Impact of neighborhood disadvantage on cardiometabolic health and cognition in a community‐dwelling cohort
1 INTRODUCTION Stark disparities exist in the prevalence of Alzheimer's disease (AD) based on socioeconomic status and poverty,1 with numerous studies demonstrating that inequitable access to socioeconomic assets such as education, employment, income, and housing is associated with an increased risk for AD and AD-related dementias (ADRD).2 Additionally, significant disparities in the incidence of dementia exist based on race and ethnicity, with consistently higher incidence rates among Black...
Family history & QoL in patients with plaque psoriasis
Fan Jiang, Lingyi Lu, Sihan Wang, Feng Yuan, Lu Cao, Suling Xu,* Bingjiang Lin* Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang; National Clinical Medical Research Center for Skin and Immune Diseases, Beijing, People’s Republic of China *These authors contributed equally to this work Correspondence: Suling Xu; Bingjiang Lin, Department of Dermatology, The First Affiliated Hospital of Ningbo University, No. 59 Liuting Street, Ningbo,...
Nickel-Catalyzed 8-Aminoquinoline Directed Reductive Dialkylcyclization/Homodialkylation of Unactivated Alkenes
Chemo and regioselective dialkylation of alkene is an efficient protocol for constructing useful chemicals, but challenges remain in the unrestricted application of alkylating reagents. Alkyl bromide belongs to the easy-to-access and operable alkyl electrophiles that can be used in reductive coupling with alkenes.
Photoredox catalysis in alkene and alkyne alkylsulfonylations: the construction of Markovnikov selective α-sulfones
Photoredox catalysis in alkene and alkyne alkylsulfonylations: the construction of Markovnikov selective α-sulfones† Photoredox alkene or alkyne alkylsulfonylation has been achieved with phthalimide esters and sulfinates providing unexpected α-sulfones. Mechanistic studies disclose that the preferential alkyl radical addition to the alkene or the Markovnikov hydrosulfonation of the alkyne should contribute to the formation of the β-alkylated α-sulfones.
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