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Abstract Objective: To examine the cross-sectional association between the triglyceride–glucose (TyG) index and the severity of lower extremity arterial disease (LEAD) in hospitalized patients with angiographically confirmed LEAD, to test whether this association differs across Glucose Metabolic States, and to quantify the ability of the TyG index to discriminate prevalent ischemic tissue loss (Rutherford grades 5–6).
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