Introduction This year commemorates the 40th birthday of the first baby born through in vitro fertilisation (IVF).1 In its infancy, IVF was a procedure with low efficiency, applied mostly in women with tubal pathology and performed against the odds.2 In 1992, the introduction of intracytoplasmic sperm injection (ICSI) assisted men with poor semen quality to father a child.3 In the following decades, the effectiveness of IVF improved, with optimised stimulation, monitoring, and lab techniques...