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Articles by Louis J. Papa
Atopic Dermatitis Care: Is It Time to Call a Specialist?
The growing number of advanced treatment options for atopic dermatitis (AD) is prompting primary care providers to partner with specialists "early and often," comments Dr Christopher Bunick, a dermatologist from Yale School of Medicine. Dr Louis Papa, a primary care physician from Rochester, New York, agrees that AD practice is becoming more cooperative, adding that he frequently contacts a dermatologist or allergist when an AD patient is not responding to first-line treatments.
Prevention and Impact of Respiratory Syncytial Virus
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An Adaptable Platform for Directed Evolution in Human Cells
Abstract The discovery and optimization of biomolecules that reliably function in metazoan cells is imperative for both the study of basic biology and the treatment of disease. We describe the development, characterization, and proof-of-concept application of a platform for directed evolution of diverse biomolecules of interest (BOIs) directly in human cells.
A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo
Laboratory time scale evolution in vivo relies on the generation of large, mutationally diverse gene libraries to rapidly explore biomolecule sequence landscapes. Traditional global mutagenesis methods are problematic because they introduce many off-target mutations that are often lethal and can engender false positives. We report the development and application of the MutaT7 chimera, a potent and highly targeted in vivo mutagenesis agent.
Health Checkup: Realistic resolutions are the key
For most of us, New Year’s resolutions are forgotten a few weeks after they’re made. That’s often because they’re too lofty and too hard to maintain. UR Medicine Primary Care’s Dr. Louis Papa offers a few simple steps toward better health, using resolutions that you can actually stick to by keeping them simple. A few small changes can make a big difference. 1. Shake off salt. Decrease the amount of salt you eat. Whole foods and plant-based foods are best.
‘Tis the season for colds and flu
No one escapes it. Whether it’s the hacking co-worker at the office holiday party, the hug from a runny-nosed grandchild, or the feverish cousin next to you at dinner, you just know you are going to get sick. We all know — and detest — the signs of the common cold: nasal symptoms, sore throat, cough, congestion, body aches, headache, sneezing, low-grade fever, and generally feeling crummy. Despite all the advances in modern medicine, the common cold continues to plague mankind.
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