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Abstract Epidemiological studies link kidney function to Parkinson’s disease risk, but the genetic basis of this relationship remains unclear. Here, we leverage genome-wide association data for Parkinson’s disease and five UK Biobank-derived kidney-related traits in individuals of European ancestry, combining genetic correlation, pleiotropy mapping, colocalization and enrichment across sex-combined and sex-stratified analyses.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.