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Transposition of the great arteries (TGA) with a systemic right ventricle (sRV) and biventricular physiology is associated with increased morbidity and mortality. There is a paucity of data regarding sex-related differences in outcomes in the context of a sRV. Moreover, pregnancy has been associated with deterioration of sRV function in short-term post-partum follow-up, but the long-term impact remains largely unknown.
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Tetralogy of Fallot (TOF) accounts for 10% of all congenital heart disease (CHD), but less than 10% of non-syndromic TOF have a known genetic etiology. TOF is an important cause of adverse right ventricular remodelling (aRVM) and dysfunction. No medical therapies have been proven to be effective after dysfunction occurs.
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