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Previous article in issue: Letter: biologics treatment in Crohn's disease and risk of bowel resection—what about the patients who stop anti-TNF therapy? Previous article in issue: Letter: biologics treatment in Crohn's disease and risk of bowel resection—what about the patients who stop anti-TNF therapy?
TNF inhibitors (TNFi) have been shown to reduce the need for surgery in Crohn's disease, but few studies have examined their effect beyond the first year of treatment. To conduct a register-based observational cohort study in Sweden 2006-2014 to investigate the risk of bowel resection in bowel surgery naïve TNFi-treated Crohn's disease patients and whether patients on TNFi ?12 months are less likely to undergo bowel resection than patients discontinuing treatment before 12 months.
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