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1 Introduction Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder marked by symptoms including abdominal pain, bloating, and changes in bowel habits (Huang et al. 2023). Affecting a large segment of the global population, IBS presents a substantial burden on individual health and healthcare systems (Huang et al. 2023).
Highlights • EGF and PDGF expression is increased in PFMCs of patients with endometriosis. • Vitamin D3 markedly decreases EGF and MDGF expression in endometriosis. • Vitamin D3 has an in-vitro inhibitory effect on PDGF expression at 6 hours following treatment, but not at 24 h or 48 h time points. Abstract Research Question : Endometriosis, an inflammatory disease, is assumed to be associated with an increase in the production of growth-related cytokines.
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