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Research Article A.D. Reed, M.A. Nethery, A. Stewart, R. Barrangou, C.M. Theriot DOI: 10.1128/JB.00039-20 ABSTRACT Clostridioides difficile is one of the leading causes of antibiotic-associated diarrhea. Gut microbiota-derived secondary bile acids and commensal Clostridia that encode the bile acid inducible (bai) operon are associated with protection from C. difficile infection (CDI), although the mechanism is not known.
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