Key words atopic dermatitis breastfeeding dupilumab pregnancy severe Abbreviations used: AD (atopic dermatitis), IL (interleukin), Th1 (T-helper), TNF (tumor necrosis factor) Introduction Atopic dermatitis (AD) is an inflammatory skin condition affecting 3% to 10% of adults and 10% to 20% of children globally. Systemic therapies such as cyclosporine, methotrexate, azathioprine, and mycophenolate mofetil have variable levels of efficacy and potential adverse effects. 3 Ponticelli C. Moroni G.
