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Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Wu X, Goebbels M, Debski-Antoniak O, Marougka K, Chao L, Smits T, et al. (2024) Unraveling dynamics of paramyxovirus-receptor interactions using nanoparticles displaying hemagglutinin-neuraminidase. PLoS Pathog 20(7): e1012371.
Sialidase-dependent and independent virion release The presence of a 2SBS in NDV (Fig 3A) allowed us to study virion release in the presence and absence of sialidase activity. To this end, NDV was bound to the 3’S(LN)2-PAA-coated sensors in the presence of BCX2798 (Fig 9A). Next, sensors were moved to wells containing PBS (with or without BCX2798) and virus dissociation was monitored.
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