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Abstract Indigenous people are disproportionately impacted by influenza viruses and chronic multimorbidity. Yet, the impact of comorbidities on immunity towards influenza vaccination is unknown. We recruited Australian First Nations and non-Indigenous people vaccinated with seasonal inactivated influenza vaccines and assessed their humoral and cellular responses in the context of comorbidities at baseline and after immunisation.
Abstract Influenza exposures early in life are believed to shape future susceptibility to influenza infections by imprinting immunological biases that engender differential cross-reactivity to future influenza viruses, but direct serological evidence linked to susceptibility is limited.
Genetic Diversity and Evolution Michelle Wille, Malet Aban, Jing Wang, Nicole Moore, Songhua Shan, John Marshall, Daniel González-Acuña, Dhanasekaran Vijaykrishna, Jeff Butler, Jianning Wang, Richard J. Hall, David T. Williams, Aeron C. Hurt Stacey Schultz-Cherry, Editor DOI: 10.1128/JVI.00271-19 ABSTRACT Wild birds harbor a huge diversity of avian avulaviruses (formerly avian paramyxoviruses).
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