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Abstract Breast cancer endocrine therapy, including tamoxifen, systemically disrupts estrogen receptor signaling and increases type 2 diabetes (T2D) risk in women. Hyperplastic adipose tissue expansion, especially in subcutaneous depots, facilitates nutrient storage and attenuates inflammation during a chronic positive energy balance and is impaired in the absence of estrogen.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
