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AR androgen receptor BCG Bacillus Calmette–Guérin IHC immunohistochemistry MIBC muscle invasive bladder cancer NMIBC non-muscle invasive bladder cancer PCR polymerase chain reaction 1 Introduction Bladder urothelial carcinoma represents a significant global health burden, with over 600 000 new cases and 220 000 deaths reported in 2022 [1]. It is the ninth most commonly diagnosed cancer worldwide [1].
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