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Manuel Tena-Semper

As seen in: Cell Metabolism
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Articles by Manuel Tena-Semper

Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice

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By Ludovica Cotellessa, Verónica Sobrino, Mauro S.B. Silva, Maxime Delit, Hélène Maitre, Émilie Caron, Gaetan Ternier, Tori Lhomme, Frank Giton, Andrea Sorrentino, Laura Carraresi, Giovanna Di Nardo, Rubén Nogueiras, Manuel Tena-Sempere, Vincent Prevot, Paolo Giacobini, Manuel Tena-Semper
| Cell Metabolism Verified
Keywords PCOS minipuberty AMH AMHR2 GnRH gonads adipose tissue hypothalamus anti-AMHR2 Introduction Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine condition, affecting up to 13% of women of reproductive age worldwide, and is characterized by a range of endocrine, reproductive, metabolic, and psychological abnormalities.1,2 The origin of PCOS is largely unknown, leaving treatment limited to symptom management without a cure.3 Thus, there is an urgent need to design effective...
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