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1 Introduction Root canal therapy (RCT) is the established treatment for pulpal and periapical diseases, requiring meticulous performance of accurate preoperative diagnosis, access cavity preparation, canal shaping, disinfection, obturation, and thorough postoperative review to achieve successful outcome (Duncan et al. 2023; Gulabivala and Ng 2023).
Sahng G. Kim and Prasanna Neelakantan were contributed equally to this work. S. G., P.Neelakantan, and M.Yang. 2026. “Microenvironmental Challenges in Regenerative Endodontic Procedures: Disinfection, Tissue Engineering and Future Directions.” International Endodontic Journal1–21. Kim, https://doi.org/10.1111/iej.70139. Conflicts of Interest The authors declare no conflicts of interest.
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