Skip To Main Content
Marcel Streit on Muck Rack

Marcel Streit

As seen in: Nature, Wiley Online Library, BioRxiv
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile
Back to Marcel Streit’s profile

Articles by Marcel Streit

Back Cover: Coronaviruses Use ACE2 Monomers as Entry‐Receptors (Angew. Chem. Int. Ed. 30/2023)

|
By Patrick Eiring, Teresa Klein, Simone Backes, Marcel Streit
| Wiley Online Library Verified
Graphical Abstract A coronavirus (round particles) carrying trimeric spike proteins infects a host cell that expresses monomeric ACE2 receptors. The low density of ACE2 receptors on the cell membrane demonstrates that on average only one spike protein per virus particle can bind to an ACE2 receptor simultaneously, which provides SARS-COV-2 a high infectivity. After binding, the membranes fuse and viral components are released into the cell, as reported by Gerti Beliu, Markus Sauer et al.
Open in Who Shared Issue with article?

Coronaviruses Use ACE2 Monomers as Entry‐Receptors

|
By Patrick Eiring, Teresa Klein, Simone Backes, Marcel Streit
| Wiley Online Library Verified
Graphical Abstract dSTORM imaging shows that the entry-receptor ACE2 of coronaviruses is homogeneously distributed in the plasma membrane of host cells with expression levels of only 1–2 ACE2 molecules μm−2. In contrast to previous reports that suggested binding of multiple spikes per virus to ACE2 homodimers or oligomers our data reveal that ACE2 is expressed as monomer in the plasma membrane in the absence and presence of trimeric spike proteins.
Open in Who Shared Issue with article?

Coronaviruses use ACE2 monomers as entry receptors

|
By Patrick Eiring, Marcel Streit, Teresa Klein, Simone Backes
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
Open in Who Shared View Duplicates (697) Issue with article?

Photoswitching fingerprint analysis bypasses the 10-nm resolution barrier - Nature Methods

|
By Gerti Beliu, Alexander C. Kuhlemann, Markus Sauer, Mara Meub, Marcel Streit
| Nature Verified
Abstract Advances in super-resolution microscopy have demonstrated single-molecule localization precisions of a few nanometers. However, translation of such high localization precisions into sub-10-nm spatial resolution in biological samples remains challenging. Here we show that resonance energy transfer between fluorophores separated by less than 10 nm results in accelerated fluorescence blinking and consequently lower localization probabilities impeding sub-10-nm fluorescence imaging.
Open in Who Shared Issue with article?
Show More