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Op-Med is a collection of original articles contributed by Doximity members. Retinitis pigmentosa (RP) is a group of inherited retinal degenerative diseases with a prevalence of approximately 1:4000, affecting 2 million persons globally. RP is genetically heterogeneous (associated with >3000 mutations in ~100 genes). Currently, there are more than 50 retinal gene therapy, clinical trials, most of which are for relatively rare diseases such as RP.
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