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Abstract Objective: To assess the accuracy of PIM-3 score in predicting neonatal mortality by comparing it to two established neonatal mortality scores, SNAPPE II and SNAP II. Study design: Retrospective study of all admissions to Great Ormond Street Neonatal Intensive Care Unit (NICU) for the calendar year of 2022. Individual scores were calculated for all admissions using the electronic health records and referring or transfer notes. Admissions <12 h and those with missing data were excluded.
Aim Five to thirty percent of neonates with trisomy 21 develop transient abnormal myelopoiesis (TAM) with a high mortality rate. The aim of the study was to identify contributing factors that determine mortality and need for chemotherapy in this patient group. Methods Six-year, single-centre, retrospective study of neonatal TAM cases requiring admission to intensive care. Data were collected from electronic patient records, laboratory and genetic results.
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