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Disclosure The authors have nothing to report. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement All analysis codes, including ICA-PLS preprocessing, wavelet denoising, MCR-ALS spectral unmixing, and Random Forest classification, are available on GitHub (link) (https://github.com/iftesummaria/Raman-Spectroscopy-for-Prostate-Cancer-using-Clinical-FFPE-Samples).
Abstract Liquid interfaces facilitate the organization of nanometer-scale biomaterials with plasmonic properties suitable for molecular diagnostics. Using hierarchical assemblage of 2D hafnium disulfide nanoplatelets and zero-dimensional spherical gold nanoparticles, the design of a multifunctional material is reported. When the target analyte is present, the nanocomposites’ self-assembling pattern changes, altering their plasmonic response.
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