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Abstract To explore the potential of an adult rabbit descemetorhexis model to recapitulate the damage to the endothelium and Descemet’s membrane (DM) seen in humans. Five corneas of 5 female New Zealand rabbits aged 24–26 months underwent 5-mm descemetorhexis; five unwounded corneas from 5 rabbits served as controls. Animals were followed up for 12-week and post-surgical clinical evaluation was performed using slit-lamp, macro images, and optical coherence tomography (OCT).
Bipyramidal gold nanoparticles-assisted plasmonic photothermal therapy for ocular applications† Gold nanoparticles (AuNPs) play a key role in the field of nanomedicine due to their fascinating plasmonic properties as well as their great biocompatibility. An intriguing application is the use of plasmonic photothermal therapy (PPTT) mediated by anisotropic AuNPs irradiated with a near-infrared (NIR) laser for treating ocular diseases in ophthalmology.
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