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Abstract Cardiac surgery with cardiopulmonary bypass (CPB) is associated with systemic metabolic alterations related to stress and immune responses. We aimed to map these dynamics through perioperative metabolomics. Furthermore, we assessed whether baseline metabolites predict postoperative outcomes. Plasma was sampled pre- and post-surgery in a discovery (n = 98) and validation cohort (n = 24). Targeted metabolomics was performed with the Biocrates MxP Quant 500XL kit.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
