Introduction Click to copy section linkSection link copied! Attenuated Listeria monocytogenes (Lmat) has been widely investigated as an anticancer vaccine, because of its ability to trigger a strong and pleiotropic immune response against primary tumors, as well as metastases. In addition, it can spread from cell to cell, reaching even the deepest, most hypoxic tumor regions. Finally, Lmat does not induce a strong antibody production; therefore, it is suitable for repeated injections.