Martin Read
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I edit @Facilitate_Mag – the magazine of the Institute of Workplace and Facilities Management (@IWFM_UK). Editor of the Year 2020 at the @memcomUK awards
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Articles by Martin Read
Roffey win at Bognor to return to top – Horsham beaten at Haywards Heath
Horsham were in a strong position with both bat and ball but paid the penalty for a mid-innings collapse, losing by one wicket in a low scoring game at Haywards Heath. Bognor put Roffey in and had them 39-2 with prolific openers Matt Davies and Fin Roberts both gone, but 33 from Jabe Rogers steadied the ship before Andrew Rambaran and Ben Remfry (60) put on 164 for the fourth wicket.
Towards enhancing sodium iodide symporter function in thyroid cancer: HiBiT tagging and CRISPR-driven drug discovery
SFEBES2025 Oral Communications Thyroid (6 abstracts) Towards enhancing sodium iodide symporter function in thyroid cancer: HiBiT tagging and CRISPR-driven drug discovery
Communities of practice in residential aged care: A rapid review
What does this research add to existing knowledge in gerontology? This paper summarises how CoPs have been developed and maintained in residential aged care to improve care quality and educate aged care workers. The studies included in this review show how the key features of a CoP ‘domain’, ‘community’ and ‘practice’ can be operationalised in residential aged care. This paper reports on various evaluations of CoPs in aged care.
Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy
Abstract The sodium/iodide symporter (NIS) frequently shows diminished plasma membrane (PM) targeting in differentiated thyroid cancer (DTC), resulting in suboptimal radioiodide (RAI) treatment and poor prognosis. The mechanisms which govern the endocytosis of NIS away from the PM are ill-defined. Here, we challenged the hypothesis that new mechanistic understanding of NIS endocytosis would facilitate prediction of patient outcomes and enable specific drug modulation of RAI uptake in vivo.
Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter
Highlights • YFP biosensor identifies FDA-approved drugs that increase intracellular iodide • Proteostasis pathways central to control of NIS symporter activity are identified • A 13-gene risk score classifier predictive of thyroid cancer recurrence is devised • A model for targetable steps of intracellular processing of NIS is proposed Summary The sodium iodide symporter (NIS) functions to transport iodide and is critical for successful radioiodide ablation of cancer cells.
Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake
Translational Science Alice Fletcher, Martin L. Read, Caitlin E.M. Thornton, Dean P. Larner, Vikki L. Poole, Katie Brookes, Hannah R. Nieto, Mohammed Alshahrani, Rebecca J. Thompson, Gareth G. Lavery, Iñigo Landa, James A. Fagin, Moray J. Campbell, Kristien Boelaert, Andrew S. Turnell, Vicki E. Smith and Christopher J. McCabe DOI: 10.1158/0008-5472.CAN-19-1957 Published January 2020 This article requires a subscription to view the full text.
Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake
Translational Science Alice Fletcher, Martin L. Read, Caitlin E.M. Thornton, Dean P. Larner, Vikki L. Poole, Katie Brookes, Hannah R. Nieto, Mohammed Alshahrani, Rebecca J. Thompson, Gareth G. Lavery, Iñigo Landa, James A. Fagin, Moray J. Campbell, Kristien Boelaert, Andrew S. Turnell, Vicki E. Smith and Christopher J. McCabe DOI: 10.1158/0008-5472.CAN-19-1957 Abstract The sodium iodide symporter (NIS) is required for iodide uptake, which facilitates thyroid hormone biosynthesis.
Targeting novel sodium iodide symporter interactors ADP-ribosylation factor 4 (ARF4) and valosin-containing protein (VCP) enhances radioiodine uptake
Research Article Alice Fletcher, Martin L Read, Caitlin E.M. Thornton, Dean P Larner, Vikki L Poole, Katie Brookes, Hannah R Nieto, Mohammed Alshahrani, Rebecca J Thompson, Gareth G Lavery, Iñigo Landa, James A. Fagin, Moray J Campbell, Kristien Boelaert, Andrew S Turnell, Vicki E. Smith and Christopher J McCabe DOI: 10.1158/0008-5472.CAN-19-1957 Abstract The sodium iodide symporter (NIS) is required for iodide uptake which facilitates thyroid hormone biosynthesis.
The Christmas Life
The Christmas Life sheet music - 2-part choir sheet music by Martin Read: Banks Publications. Shop the World's Largest Sheet Music Selection today at Sheet Music Plus.
PTTG and PBF Functionally Interact with p53 and Predict Overall Survival in Head and Neck Cancer
PTTG and PBF Functionally Interact with p53 and Predict Overall Survival in Head and Neck Cancer Martin L. Read, Bhavika Modasia, Alice Fletcher, Rebecca J. Thompson, Katie Brookes, Peter C. Rae, Hannah R. Nieto, Vikki L. Poole, Sally Roberts, Moray J. Campbell, Kristien Boelaert, Andrew S. Turnell, Vicki E. Smith, Hisham Mehanna and Christopher J. McCabe Cancer Res October 15 2018 (78) (20) 5863-5876; DOI: 10.1158/0008-5472.CAN-18-0855
PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer
PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer Martin L Read, Bhavika Modasia, Alice Fletcher, Rebecca J Thompson, Katie Brookes, Peter C Rae, Hannah R Nieto, Vikki L Poole, Sally Roberts, Moray J Campbell, Kristien Boelaert, Andrew S Turnell, Vicki E. Smith, Hisham Mehanna and Christopher J McCabe Cancer Res August 28 2018 DOI: 10.1158/0008-5472.CAN-18-0855
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