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Abstract Edematous severe childhood malnutrition is distinct from the non-edematous form of malnutrition and remains a major cause of under-five mortality. Its etiology remains unclear, although aberrant one-carbon metabolism has emerged as a potential contributor. Here, we assess genetic variants at loci known to influence one-carbon metabolism, and determine their association with edematous malnutrition in Jamaica and Malawi.
Ayuda Buscar en la ayuda Buscar en la ayuda Management of diabetes mellitus in three settings in Jamaica Rainford J. Wilks [1] ; Lincoln A. Sargeant [1] ; Martin C. Gulliford [2] ; Marvin E. Reid [1] ; Terrence E. Forrester [1] [1] University of the West Indies [2] King's College City of Wilkes-Barre, Estados Unidos Localización: Revista Panamericana de Salud Pública = Pan American Journal of Public Health, ISSN-e 1680-5348, ISSN 1020-4989, Vol. 9, Nº.
To explore putative associations between specific variants in either the glutathione S-transferase (GST), haptoglobin (HP), or uridine 5?-diphospho-glucuronosyltransferase 1A1 (UGT1A1) genes and clinically important phenotypes in sickle cell anaemia (HbSS). Three hundred and seventy-one HbSS participants were recruited from the Sickle Cell Clinic of the Sickle Cell Unit at the University of the West Indies, Kingston, Jamaica.
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