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Accepted manuscript, PDF only. Full online edition to follow. Accepted Manuscript November 1, 2024 Share this article Cite this article Distinct functions of three Wnt proteins control mirror-symmetric organogenesis in the C. elegans gonad eLife 13:e103035. https://doi.org/10.7554/eLife.103035 Data availability All data generated or analysed during this study are included in the manuscript and supporting files; source data files have been provided for Figures 3 and 4.
Abstract Organogenesis requires the proper production of diverse cell types and their positioning/migration. However, the coordination of these processes during development remains poorly understood. The gonad in C. elegans exhibits a mirror-symmetric structure guided by the migration of distal tip cells (DTCs), which result from asymmetric divisions of somatic gonadal precursors (SGPs; Z1 and Z4).
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