Cell Stem Cell
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Cell Stem Cell is a peer-reviewed scientific journal published by Cell Press, an imprint of Elsevier. The journal was established in 2007 and focuses on stem cell research. Both research articles and reviews are published, at about a 7 to 1 ratio. Source
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| Scope | International |
|---|---|
| Language | English |
| Country | United States of America |
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| Accepts contributed content | Yes |
Recent Articles
Search ArticlesGeneration of spermatogonia from human and non-human primate pluripotent stem cells
STAR★Methods REAGENT or RESOURCESOURCEIDENTIFIER Antibodies Chicken anti-GFP Abcam ab13970; RRID: AB_300798 Goat anti-NANOG R&D Systems AF1997; RRID: AB_355097 Goat anti-SOX17 R&D SYSTEMS AF1924; RRID: AB_355060 Goat anti-CD31 R&D Systems AF3628; RRID: AB_2161028 Goat anti-DDX4 R&D Systems AF2030; RRID: AB_2277369 Goat anti-UTF1 R&D Systems AF3958; RRID: AB_2304316 Mouse anti-ACTA2 Abcam ab7817; RRID: AB_262054 Mouse anti-GFRA1 R&D Systems MAB7141; RRID: AB_2263326 Mouse anti-human...
FDA-approved fulvestrant-induced CAR phase separation enables precise control of CAR T antitumor function
Keywords CAR T cell therapy liquid-liquid phase separation tonic signaling fulvestrant Get full text access Log in, subscribe or purchase for full access. References 1. Chen, Y.H. ∙ Zhang, X. ∙ Cheng, Y.F. ... Long-term follow-up of CD19 chimeric antigen receptor T-cell therapy for relapsed/refractory acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation Cytotherapy. 2020; 22:755-761 2. Hay, K.A. ∙ Gauthier, J. ∙ Hirayama, A.V. ...
Patient-derived organoids reveal ductal dysfunction and CFTR-modulator responses in chronic pancreatitis
ArticleOnline nowOpen access Affiliations & Notes 1Salk Institute for Biological Studies, La Jolla, CA 92037, USA 2Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA 3Department of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA 4Schulze Diabetes Institute, Department of Surgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA 5Ariel Precision Medicine, Pittsburgh, PA 15206, USA 6Department of Surgery, Division of...
Lineage plasticity driven by GATA6 loss fuels colorectal cancer metastasis
Keywords colorectal cancer organoid metastasis Get full text access Log in, subscribe or purchase for full access. References 1. Dekker, E. ∙ Tanis, P.J. ∙ Vleugels, J.L.A. ... Colorectal cancer Lancet. 2019; 394:1467-1480 2. Siegel, R.L. ∙ Giaquinto, A.N. ∙ Jemal, A. Cancer statistics, 2024 CA A Cancer J. Clinicians. 2024; 74:12-49 3. Biller, L.H. ∙ Schrag, D. Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review JAMA. 2021; 325:669-685 4. Hu, Z. ∙ Ding, J. ∙ Ma, Z. ...
Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation
Keywords emergency myelopoiesis hematopoietic stem and progenitor cell differentiation regeneration inflammation topology quantitative model acute myeloid leukemia Get full text access Log in, subscribe or purchase for full access. References 1. Olson, O.C. ∙ Kang, Y.A. ∙ Passegué, E. Normal hematopoiesis is a balancing act of self-renewal and regeneration Cold Spring Harb. Perspect. Med. 2020; 10, a035519 2. Swann, J.W. ∙ Olson, O.C. ∙ Passegué, E.
Paired pre- and post-transplant human immunoprofiling identifies an IFN-γ-JAK1 axis limiting stem-cell-derived RPE engraftment
Keywords stem cell transplantation immune microenvironment age-related macular degeneration translational medicine retinal regeneration cell therapy graft immunogenicity immune rejection transplant immunology JAK-STAT signaling Get full text access Log in, subscribe or purchase for full access. References 1. Jin, Z.-B. ∙ Gao, M.-L. ∙ Deng, W.-L. ... Stemming retinal regeneration with pluripotent stem cells Prog. Retin. Eye Res. 2019; 69:38-56 2. Lim, L.S. ∙ Mitchell, P. ∙ Seddon, J.M. ...
ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation
Keywords genome integrity DNA repair senescence senescence-associated secretory phenotype SASP inflammation CRISPR-Cas9 screening ZNF512B chromatin remodeling amyotrophic lateral sclerosis neuromuscular organoids Get full text access Log in, subscribe or purchase for full access. References 1. Di Micco, R. ∙ Krizhanovsky, V. ∙ Baker, D. ... Cellular senescence in ageing: from mechanisms to therapeutic opportunities Nat. Rev. Mol. Cell Biol. 2021; 22:75-95 2. Eggert, T. ∙ Wolter, K. ∙ Ji, J. ...
Designing complex organoids through developmental principles
Keywords organoid assembloid self-organization developmental biology organogenesis engineering organoid Get full text access Log in, subscribe or purchase for full access. References 1. Sagner, A. ∙ Briscoe, J. Morphogen interpretation: concentration, time, competence, and signaling dynamics WIREs Dev. Biol. 2017; 6, e271 2. Hannezo, E. ∙ Heisenberg, C.-P. Mechanochemical Feedback Loops in Development and Disease Cell. 2019; 178:12-25 3. Levin, M.
Evolving strategies for lineage tracing: Genetic markers, synthetic barcodes, and natural variants
Keywords lineage tracing cell fate development regeneration diseases barcoding recombinase Introduction Cell fate dictates the developmental trajectory a cell follows—from its origin to its terminal identity—under physiological and pathological conditions.
Autologous macrophage therapy increases transplant-free survival in cirrhosis: Long-term follow-up of a phase 2 clinical trial
Keywords liver cirrhosis long-term follow-up macrophage cell therapy liver fibrosis regenerative macrophage Introduction Cirrhosis represents a major global health burden, with substantial and rising morbidity and mortality.1 Apart from liver transplantation, therapeutic options for end-stage disease remain limited to supportive care and management of complications, underscoring the urgent need for innovative approaches to halt or reverse disease progression.2 The onset of acute...