Genes and Development Journal
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Genes & Development publishes high-quality research papers of broad general interest and biological significance in the areas of molecular biology, molecular genetics, and related fields. In addition to Review Articles and Perspectives, Genes & Development publishes three research formats—Research papers, short Research Communications, and Resource/Methodology papers. Source
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| Scope | International |
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| Language | English |
| Country | N/A |
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| Accepts contributed content | Yes |
Recent Articles
Search ArticlesmRNA 3′ UTRs direct microRNA degradation to participate in imprinted gene networks and regulate growth
1,2,3 1Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA; 2Howard Hughes Medical Institute, Cambridge, Massachusetts 02142, USA; 3Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA; 4Harvard-Massachusetts Institute of Technology MD-PhD Program, Harvard Medical School, Boston, Massachusetts 02115, USA Corresponding author: dbartel{at}wi.mit.edu ↵5 These authors contributed equally to this work.
Nonhomologous end joining—the importance of end tethering and beyond
1 1Institute for Cancer Genetics, Vagelos College for Physicians and Surgeons, Columbia University, New York, New York 10032, USA; 2Herbert Irvine Comprehensive Cancer Center, Vagelos College for Physicians and Surgeons, Columbia University, New York, New York 10032, USA; 3Department of Pediatrics, Vagelos College for Physicians and Surgeons, Columbia University, New York, New York 10032, USA; 4Department of Pathology and Cell Biology, Vagelos College for Physicians and Surgeons, Columbia...
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This item requires a subscription to Genes & Development. Full Text (PDF) RESEARCH PAPER: α-Satellite RNA marks the perinucleolar compartment and represses ribosomal RNA expression in naive human embryonic stem cells , , and Genes Dev. ; doi:10.1101/gad.353162.125 To view this item, select one of the options below:
Metabolic permissiveness: how tissue context shapes cancer
1,2,3 1Faculty of Medicine and University Hospital Cologne, Institute for Metabolomics in Ageing, Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany; 2Faculty of Mathematics and Natural Sciences, Institute of Genetics, Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany; 3Center for Molecular Medicine (CMMC), University of Cologne,...
Multiomic analysis of clonal development reveals new regulators of leukemic cell growth
1,9 1Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; 2Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA; 3Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; 4Harvard Stem Cell Institute, Cambridge, Massachusetts 02138, USA; 5Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138, USA; 6Division of Infectious Diseases,...
Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
1,7,8,9 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA; 2Department of Microbiology and Molecular Biology, Chungnam National University, Daejeon 34134, Republic of Korea; 3Department of Health Data Science and Biostatistics, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA; 4Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas...
Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer
1 1Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA; 2Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; 3Graduate Group in Cancer Biology, St Joseph's University, Philadelphia, Pennsylvania 19131, USA; 4Helen F.
SOX2 phosphorylation during mitosis limits genomic damage
1,2 1Centre for Regenerative Medicine, Institute for Regeneration and Repair, Cancer Research UK Scotland Centre, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom; 2Cancer Research UK Scotland Centre, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom; 3MRC Laboratory of Medical Sciences, Imperial College London, London W12 0NN, United Kingdom Corresponding author: steven.pollard{at}ed.ac.uk Footnotes Supplemental material is available for this article.
Nuclear receptor coregulator interactions: beyond the switch
1,2 1Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; 2Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA Corresponding author: lazar{at}pennmedicine.upenn.edu Footnotes Article published online ahead of print.
Potent synthetic lethality between PLK1 and EYA family inhibitors in tumors of the central and peripheral nervous systems
1 1Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, New South Wales 2145, Australia; 2Department of Chemistry, University of Colorado, Boulder, Colorado 80309, USA; 3Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA Corresponding author: hpickett{at}cmri.org.au ↵4 These authors contributed equally to this work. Footnotes Supplemental material is available for this article.