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Psoriasis Area and Severity Index Use in Pediatric Psoriasis
The Psoriasis Area and Severity Index (PASI) scoring system was formulated to quantify adult psoriasis disease burden in clinical trials.1 A patient’s PASI score is reported as a number between 0 and 72, with a score between 5 and 10 considered moderate. A score greater than 10 signifies that the disease is severe.2 The score is calculated by assessing the head, upper extremities, trunk, and lower extremities for erythema, induration, and scaling.
Age- and Sex-Related Differences in Primary Cutaneous Lymphoma
Non-Hodgkin lymphomas (NHLs) are a heterogeneous group of lymphoproliferative malignancies originating from T, B, or natural killer (NK) lymphocytes.1 Compared to Hodgkin lymphomas, NHLs exhibit a broader clinical spectrum and have a poorer prognosis and frequent extranodal involvement, with the skin being the second most frequent extranodal site.2 Primary cutaneous lymphomas (PCLs) are NHLs that are first evident on the skin without evidence of extracutaneous disease at diagnosis.
The Hair-Cut Sign for Scalp Biopsy Site Identification
Accurate biopsy site identification prior to Mohs micrographic surgery (MMS) can be challenging, particularly on the scalp, where excellent healing, field cancerization, prior procedures, large surface area, and hair density may complicate localization. Accurate site identification is further hindered when patients are unable to recall the biopsy location, when the biopsy and MMS are performed by different clinicians, or when photographic documentation is absent.
Topical Hypochlorous Acid for Acne Vulgaris: Mechanisms, Clinical Evidence, and Therapeutic Potential
Acne vulgaris, a chronic inflammatory disease of the pilosebaceous unit, is among the most prevalent dermatologic conditions worldwide. Though symptoms range in severity, patients can experience painful irritation and scarring that can lead to substantial psychological distress and impact quality of life.
Optimizing Clinical Teams in Dermatology: A Strategic Framework for Recruitment, Onboarding, and Retention
Effective staffing is central to delivering high-quality, efficient dermatologic care. In the current landscape of American medicine, dermatologists manage complex medical conditions, perform surgical procedures, and in some cases expand into elective aesthetic services. The ability to offer advanced clinical services is dependent on the performance of those who operate equipment and sustain daily operations.
Rosacea: We Still Haven’t Found What We’re Looking For
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Pembrolizumab-Induced Bullous Pemphigoid: Navigating Diagnostic Challenges and Treatment Resistance
Bullous pemphigoid (BP) is an autoimmune blistering disorder characterized by the development of tense subepidermal blisters and erosions primarily on the skin, commonly affecting the elderly.1 It is attributed to autoantibodies targeting 2 hemidesmosomal components within the dermoepidermal junction—transmembrane collagen XVII (BP180/BPAG2) and plakin family protein BP230 (BPAG1)—resulting in blister formation due to loss of structural integrity.2 Typically, patients present with pruritic...
Cemiplimab for Unresectable Cutaneous Squamous Cell Carcinoma: Experience From a Tertiary Center
Cutaneous squamous cell carcinoma (cSCC) is the second most prevalent skin cancer and ranks sixth in prevalence among all cancers in the United Kingdom.1,2 The etiologic factors underlying cSCC are well established, with major efforts undertaken by governments and public health organizations over the past 2 decades to increase public awareness globally. Known risk factors for cSCC include chronic exposure to UV radiation, radiotherapy, chemical injury, and immunosuppression.
A Cost-Effectiveness and Psychological Evaluation of Early Skin Biopsies vs Later-Onset Surgeries in Melanoma Management
Compared to later-onset procedures, early diagnosis of melanoma using affordable skin biopsies can result in better patient outcomes, lower health care expenditures, and enhanced psychological well-being.1 Numerous research and economic evaluations that highlight the possible advantages of early intervention in melanoma care lend support to this strategy.