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Abstract Background and aims: Gut microbiota and intestinal permeability may play a role in food specific IgG antibodies mediated delayed hypersensitivity in migraine patients. We aimed to evaluate the effect of food specific IgG-guided elimination strategy by assessing the changes in gut microbiota, zonulin as well as their correlation with symptoms, IL-6, TNF-α and CGRP.
BMI Body mass index COVID-19 Corona Virus Disease 2019 ELISA enzyme linked immunosorbant assay GSRS Gastrointestinal Symptom Rating Scale HIT-6 Headache Impact Test-6 IgG Immunoglobulin G MIDAS Migraine Disability Assessment questionnaire MSQ Migraine-Specific Quality of Life Questionnaire PSQI Pittsburgh Sleep Quality Index SAS Self-Rating Anxiety Scale SDS Self-Rating Depression Scale VAS Visual Analog Scale 1 Introduction Migraine is the second most common neurological disorder in the world.
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