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Abstract SIRT1 is an NAD+-dependent deacetylase involved in the maintenance and differentiation of neural stem cells (NSCs). Although alternative splicing increases the regulatory complexity of SIRT1, its splice isoforms in the rat nervous system remain poorly defined. This study aimed to identify SIRT1-ΔExon8 in rats, characterize its regional expression, and assess its association with NSC differentiation.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
