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Abstract Background: Lower respiratory infection (LRI) remains an important cause of death and health loss in children younger than 5 years. We examined the residual global and Chinese under-5 LRI burden, vaccine-relevant pathogen inequalities, and the separate clinical-care needs of children hospitalized with pneumonia in China.
Abstract Low-intensity extracorporeal shock wave therapy (Li-ESWT) has demonstrable mechanobiologic activity in nonpulmonary systems, where it has been linked to adenosine triphosphate (ATP) release and downstream signaling, macrophage and fibroblast responses, matrix remodeling, and tissue repair. Whether those effects extend to pediatric respiratory disease is uncertain.
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