Introduction Enterococci are a group of low-GC Gram-positive cocci that comprise up to 60 different species (Cattoir, 2022). Among these species, Enterococcus faecalis and Enterococcus faecium are the two main species that have become a leading cause of human infections (Jabbari Shiadeh et al., 2019; Bright et al., 2020; Kakoullis et al., 2021). In recent years, the rise of vancomycin-resistant Enterococcus (VRE) has become a growing threat in hospital settings, and E.