The ovary is central to female reproductive and endocrine health throughout the lifespan. Beyond its essential roles in follicular development, ovulation, and steroidogenesis, the age-related loss of ovarian function is accompanied by progressive depletion of the follicular reserve, deterioration of oocyte quality, and endocrine decline, with consequences extending beyond fertility to broader aspects of women's health (Ahlborg et al. 2001; Galatidou et al. 2024; Hansen et al. 2008; Smits et al.