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Abstract The rise of Klebsiella pneumoniae combining antimicrobial resistance and virulence genes poses a major health threat, but the evolutionary routes and phenotypic consequences of this convergence are poorly understood. Here, phylogenetics of 1468 isolates and population analysis of 7520 plasmids, from >50 countries through the last two decades, reveal that convergence follows preferred, constrained evolutionary paths. The dominant route involves multidrug-resistant classical K.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
