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Michael B. Prystowsky on Muck Rack

Michael B. Prystowsky

As seen in: Nature, Archives of Pathology, The Pathologist
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Articles by Michael B. Prystowsky

The deep learning framework Hist2Prot infers single-cell spatial proteomics from histology to predict biomarkers and clinical outcomes

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By Jiansong Fan, Erqiang Hu, Jianhong An, Qiang Liu, Naijia Liu, Mingwei Ma, Michael B. Prystowsky, Tianxu Lv, Yuting Ren, Yuan Liu, Lihua Li, Yuan Li, Qi Sun, Pengjiang Qian, Le Lu, Wenjun Deng, Xiang Pan, Shanye Yin
| Nature Verified
Abstract Spatial proteomics enables high-resolution mapping of protein expression within the tumor microenvironment, but its routine clinical application remains limited by cost, technical complexity and restricted tissue coverage. Here we present Hist2Prot, a deep learning framework that generates single-cell spatial proteomic profiles from routine hematoxylin and eosin histology.
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Healthcare Access for All

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By Michael B. Prystowsky
| The Pathologist Verified
My travels to international scientific meetings and inspections of clinical laboratories from India to Guantanamo Bay over the years have shown me a diversity of healthcare systems. These experiences have opened my eyes to the social and economic challenges faced by underserved communities across the globe – and the resulting inequities in their access to quality healthcare.
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Answering the Call

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By Michael B. Prystowsky, Jacob Steinberg Verified, Adam Cole, Tiffany Hebert
| The Pathologist Verified
Professional opportunities to practice pathology vary worldwide. In Europe and the Middle East, most positions are for either an anatomic pathologist or a laboratorian directing clinical laboratories. Residency training reflects these opportunities. Although these career paths exist in the United States, there is also substantial opportunity to practice pathology in a community hospital – a job that requires expertise in both anatomic pathology and laboratory medicine.
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