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Michael Mach

As seen in: American Society for Microbiology (ASM)
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Articles by Michael Mach

Human Cytomegalovirus Envelope Protein gpUL132 Regulates Infectious Virus Production through Formation of the Viral Assembly Compartment

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By Barbara Kropff, William Britt, Thomas Shenk, Michael Mach
| American Society for Microbiology (ASM)
Research Article | Host-Microbe Biology Hui Wu, Barbara Kropff, Michael Mach, William J. Britt Thomas Shenk, Editor DOI: 10.1128/mBio.02044-20 ABSTRACT The human cytomegalovirus (HCMV) UL132 open reading frame encodes a 270-amino-acid type I envelope glycoprotein, gpUL132. The deletion of UL132 (ΔUL132) from the HCMV genome results in a pronounced deficit in virus yield, with an approximately 2-log decrease in the production of infectious virus compared to the wild-type (WT) virus.
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