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Michelle T. Ji

As seen in: Wiley Online Library, BioRxiv
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Articles by Michelle T. Ji

Early onset memory deficit of WMI rats compared to their nearly isogenic WLIs is reversed by enriched environment in females

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By Michelle T. Ji, Aspen Harter, Mariya Nemesh, Katherine J Przybyl
| BioRxiv
Abstract We tested the hypothesis that environmental enrichment (EE) can attenuate early-onset cognitive decline in a stress-hyperresponsive rat strain. The novel genetic model, the Wistar Kyoto More Immobile (WMI) inbred rat strain demonstrates increased stress reactivity and enhanced depression-like behavior compared to its nearly isogenic control, the Wistar Kyoto Less Immobile strain (WLI).
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Female Wistar Kyoto More Immobile rats with genetic stress hyper‐reactivity show enhanced contextual fear memory without deficit in extinction of fear

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By Aspen Harter, Mariya Nemesh, Michelle T. Ji, Luca Lee
| Wiley Online Library Verified
ANOVA analysis of variance CFC contextual fear conditioning CORT corticosterone EDTA ethylenediaminetetraacetic acid ELISA enzyme linked immunosorbent assay Esr1 and Esr2 oestrogen receptors 1 and 2 Gapdh glyceraldehyde-3-phosphate dehydrogenase Glut1 glucose transporter isoform 1 GR glucocorticoid receptor GTT intraperitoneal glucose tolerance test HPA hypothalamic–pituitary–adrenal Nr3c1 nuclear receptor subfamily 3 group C member 1 PTSD posttraumatic stress disorder RQ relative...
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