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AHR aryl hydrocarbon receptor DC dendritic cell HC healthy control IDO1 indoleamine 2,3-dioxygenase 1 LP lupus panniculitis PRR pattern recognition receptor Th T helper 1 Introduction Panniculitis is the clinical correlate of subcutaneous adipose tissue (SWAT) inflammation and encompasses a wide spectrum of conditions varying in severity and cause. It can result from infections, tumors, autoimmune, or inflammatory diseases [1].
Background Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a rare, severe delayed-type drug hypersensitivity reaction. It can range from mild reactions with little or no organ involvement to severe, potentially life-threatening forms. It is unclear whether these distinct clinical phenotypes are associated with different immune signatures and, ultimately, distinct pathomechanisms. Aims The aim of this study was to explore systemic immune profiles of DRESS patients.
Management of Adult Patients With Drug Reaction With Eosinophilia and Systemic Symptoms: A Delphi-Based International Consensus Autores: Marie Charlotte Brüggen, Sarah Walsh, Milad Ameri, Natalie Anasiewicz, Emanual Maverakis, Lars Einar French, Saskia Ingen-Housz-Oro Localización: JAMA Dermatology, ISSN 2168-6068, Vol. 160, Nº. 1, 2024, págs.
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