Abstract Heliopsis helianthoides is a perennial medicinal plant in the Asteraceae family, valued for its anti-inflammatory, antimicrobial, and antioxidant properties. Despite its pharmacological significance, its chloroplast genome remains uncharacterized. Here, we report the first complete chloroplast genome of H. helianthoides, which is also the first for the genus Heliopsis. The genome is 151,140 bp in length with a typical quadripartite structure, containing 127 genes and a GC content of 37.6%.
